Dynamic expression of pepsinogen C in gastric cancer, precancerous lesions andHelicobacter pyloriassociated gastric diseases
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چکیده
منابع مشابه
Expression of TERT in precancerous gastric lesions compared to gastric cancer.
The objective of this study was to determine the levels of TERT mRNA and TERT protein expression in stomach precancerous lesions such as intestinal metaplasia (IM) and gastric ulcer (GU) and compare them to gastric cancer (GC). Real-time PCR was performed to detect TERT mRNA expression levels in 35 biopsies of IM, 30 of GU, and 22 of GC and their respective normal mucosas. TERT protein was dete...
متن کاملGastric Precancerous Lesions in Relatives of Iranian Stomach Cancer Patients
Gastric cancer is a major public health as the fourth most common cancer and second leading cause of cancerrelated death in the world (De Vries et al., 2007; Motta et al., 2008; Herszényi and Tulassay, 2010; Yaghoobi et al., 2010). According to recent studies, about 7300 cases in Iran (10.5 per 100,000 individuals) are afflicted to gastric cancer annually (Mehrabian etal., 2010). The initial di...
متن کاملMicrosatellite instability of gastric cancer and precancerous lesions.
OBJECTIVE To investigate whether microsatellite instability (MSI) of gastric cancer and precancerous lesions were existed and its effect. METHODS Laser microdissection was used. Gastric, intestinal metaplasia, dysplasia and normal mucosa were collected respectively. Five microsatellite loci were selected and MSI was detected by denaturing high-performance liquid chromatography. RESULTS In t...
متن کاملExpression of the γ-phosphorylated histone H2AX in gastric carcinoma and gastric precancerous lesions
The histone γH2AX is a marker of activated DNA damage that is overexpressed in various cancers and corresponding precursor lesions, indicating that γH2AX is a component in oncogenic transformation. The present study aimed to determine whether the immunohistochemical expression of γH2AX is involved in the progression between superficial gastritis (n=20), atrophic gastritis (n=24) and gastric car...
متن کاملClinical values of gastrin 17 and pepsinogen in gastric cancer and precancerous lesion screening
Objective: This study aims to investigate the clinical significance of gastrin 17 and pepsinogen in gastric cancer and precancerous lesion screening. Methods: We used ELISA to measure the levels of gastrin 17 and pepsinogen in serum from the medical examination population, which compared to endoscopic results. Then statistical analysis was performed. Results: The classical method by testing pep...
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ژورنال
عنوان ژورنال: World Journal of Gastroenterology
سال: 2005
ISSN: 1007-9327
DOI: 10.3748/wjg.v11.i17.2545